Вход

Закрыть
Логин:
Пароль:

Intermittent hypoxia increases exercise tolerance in patients at risk for or with mild COPD
Регионы
Eng
Главная > О методе > Научные публикации > Intermittent hypoxia increases exercise tolerance in patients at risk for or with mild COPD

Intermittent hypoxia increases exercise tolerance in patients at risk for or with mild COPD

The effects of repeated short-term hypoxia on exercise tolerance in patients at risk for, or with mild COPD were investigated. Eighteen patients (10 males, 8 females; 33–72 years) were randomly assigned in a double-blind fashion to receive 15 sessions of intermittent hypoxia (FiO2: 0.15–0.12) or normoxia within 3 weeks. Three weeks of intermittent hypoxia increased total haemoglobin mass (+4% vs. 0%,p<0.05), total exercise time (+9.7% vs. 0%,p<0.05) and the exercise time to the anaerobic threshold (+13% vs.−7.8%, p<0.05) compared to controls. Changes in the total exercise time were positively related to the changes in total haemoglobin mass (r=0.59, p<0.05) and changes in the time to the anaerobic threshold were positively related to the changes in the lung diffusion capacity for carbon monoxide (r=0.48, p<0.05). Intermittent hypoxia treatment may be a valuable addition to therapy designed to improve exercise tolerance in patients at risk for, or with mild COPD.

Read more.

 

Год: 2008

Burtscher M, Haider T, Domej W, Linser T, Gatterer H, Faulhaber M, Pocecco E, Erenburg I, Tkatchuk E, Koch R, Bernardi L

Источник: Respiratory Physiology & Neurobiology